Projects

We are devoted to the development of computational algorithms for LifeScience, using molecular modelling techniques, bioinformatics and machine learning methods.

Our molecular modeling software, PELE, is used worldwide through its public server, and commercialised through NBD since 2017, and clearly outperformed other tools in the CSAR blind...

In this project, we present PluriZymes, enzymes containing multiple (engineered) catalytic actives sites in a single scaffold, as one of the next breakthroughs in enzymatic catalysis. We show clear preliminary evidence of the potential role of PluriZymes in optimizing complex biochemical processes, such as cellulose degradation, or to group cascade reactions into one single...

The INDOX proposal on industrial oxidoreductases aimed to provide relevant industrial case stories to demonstrate the efficacy of optimized biocatalysts on targeted reactions, and to establish the processes scalability, sustainability and cost-efficiency versus chemical conversion processes. The chemical industry (specialties excluded) is not yet embracing enzymatic oxidation...