Victor Guallar Tasies

2018

• Kauniolide synthase is a P450 with unusual hydroxylation and cyclization-elimination activity

  Nature Communications

  Q. Liu, A. Beyraghdar Kashkooli, D. Manzano, I. Pateraki, L. Richard, P. Kolkman, M F. Lucas, V. Guallar, R. C. H. de Vos, M. C. R. Franssen, A. van der Krol, and H. Bouwmeester
• Automated Design of Efficient and Functionally Diverse Enzyme Repertoires

  Molecular Cell

  O. Khersonsky, R. Lipsh, Z. Avizemer, iv, Y. Ashani, M. Goldsmith, H. Leader, O. Dym, S. Rogotner, D. L. Trudeau, J. Prilusky, P. Amengual-Rigo, V. Guallar, D. S. Tawfik, and S. J. Fleishman
• Description of a Non-Canonical Mn(II)-Oxidation Site in Peroxidases

  ACS Catalysis

  E. Fernández-Fueyo, I. Davó-Siguero, D. Almendral, D. Linde, M C. Baratto, R. Pogni, A. Romero, V. Guallar, and A. T. Martínez
• Pushing the Limits of Computational Structure-Based Drug Design with a Cryo-EM Structure: The Ca2+ Channel α2δ-1 Subunit as a Test Case

  Journal of Chemical Information and Modeling

  M. Kotev, R. Pascual, C. Almansa, V. Guallar, and R. Soliva
• Multiple implications of an active site phenylalanine in the catalysis of aryl-alcohol oxidase

  Scientific Reports

  J. Carro, P. Amengual-Rigo, F. Sancho, M. Medina, V. Guallar, P. Ferreira, and A. T. Martínez
• Computational structure-based drug design: Predicting target flexibility

  Wiley Interdisciplinary Reviews: Computational Molecular Science

  J. Iglesias, S. Saen-oon, R. Soliva, and V. Guallar
• Selective Synthesis of the Human Drug Metabolite 5′-Hydroxypropranolol by an Evolved Self-Sufficient Peroxygenase

  ACS Catalysis

  P. Gomezde Santos, M. Cañellas, F. Tieves, S. H. H. Younes, P. Molina-Espeja, M. Hofrichter, F. Hollmann, V. Guallar, and M. Alcalde
• Rational Engineering of Multiple Active Sites in an Ester Hydrolase

  Biochemistry

  G. Santiago, M. Martínez-Martínez, S. Alonso, R. Bargiela, C. Coscolín, P. N. Golyshin, V. Guallar, and M. Ferrer

2017

• Determinants and Prediction of Esterase Substrate Promiscuity Patterns

  ACS Chemical Biology

  M. Martínez-Martínez, C. Coscolín, G. Santiago, J. Chow, P. J. Stogios, R. Bargiela, C. Gertler, J. Navarro-Fernández, A. Bollinger, S. Thies, C. Méndez-García, A. Popovic, G. Brown, T. N. Chernikova, A. García-Moyano, G. E. K. Bjerga, P. Pérez-García, T. Hai, M. V. Del Pozo, R. Stokke, I. H. Steen, H. Cui, X. Xu, B. P. Nocek, M. Alcaide, M. Distaso, V. Mesa, A. I. Peláez, J. Sánchez, P. C. F. Buchholz, J. Pleiss, A. Fernández-Guerra, F. O. Glöckner, O. V. Golyshina, M. M. Yakimov, A. Savchenko, K-E. Jaeger, A. F. Yakunin, W. R. Streit, P. N. Golyshin, V. Guallar, M. Ferrer, and T. I. N. M. A. R. E. Consortium
• Binding of Thioflavin T and Related Probes to Polymorphic Models of Amyloid-β Fibrils

  The Journal of Physical Chemistry B

  F. Peccati, S. Pantaleone, V. Riffet, X. Solans-Monfort, J. Contreras-García, V. Guallar, and M. Sodupe