Comparative Genomics

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The recent advances in Next-Generation Sequencing (NGS) of nucleic acids (i.e. DNA or RNA) have transformed biology and medicine. Today, NGS is one of the main pillars of research in various biological disciplines and it has already pervaded numerous fields of applications ranging from the clinics to the biotechnological industry. Given its versatility and high demand, the...

The comparative genomics group ( ) is jointly affiliated to the Barcelona Supercomputing Centre (BSC) and the Biomedical Research Institute (IRB).

The main research interest of our group is to understand the complex relationships between genome sequences and phenotypes and how these two features evolve within and across species. We...

Long non-coding RNAs (lncRNAs) are abundant in mammalian transcriptomes. However, it remains unclear how many of them are functional, and how their functions are performed. LncRNAs seem to be poorly conserved at the sequence level, but some of them share conserved structural elements and are present at syntenic genomic positions in different species.