Annual Report 2008

Life Sciences Department

The BSC-CNS Life Science Department and Joint IRB-BSC Program on Computational Biology
Report of Research Activities 2008

Aims And Structure Of The Program/Department

The aim of the scientists in the Life Science Department is to understand the molecular biology and evolution of living organisms using theoretical models and simulation algorithms. The Department integrates different independent researchers led by senior scientists who work in different aspects of computational biology, ranging from bioinformatics for genomics to computational biochemistry. The department is structured as a collaborative effort with other institutions like ICREA, IRB-PCB-UB and the National Institute of Bioinformatics (INB). The Program is now coordinated with the Structural and Computational Biology Program at the Institute of Research in Biomedicine defining a Joint IRB-BSC Research Program on Computational Biology. This report traces activities of both Life Sciences Department and IRB-BSC Computational Biology Program. Major areas of research include Molecular Modelling, Structural Bioinformatics, Computational Genomics, network medicine, subatomic study of protein functions and protein-protein docking.

Research Activities 2008

Led by Modesto Orozco, the long term objective of this Group is to understand the behaviour of living organisms by means of theoretical models, whose roots are anchored in the basic principles of...
Led by Juan Fernández-Recio this Group aims to study the mechanism and function of proteins in living organisms, with a special focus on the biomolecular interactions at atomic and residue...
Led by Victor Guallar, the overall objective of this lab is to explore the chemical and physical responses to local and global configuration changes in proteins, with emphasis on substrate...
Led by David Torrents the ultimate goal of this Group’s research is the identification and understanding of the molecular and evolutionary processes that determine the biology of genomes, and...
Led by Patrick Aloy (IRB), the main scientific interests of this Group are in the field of structural bioinformatics. In particular, on the use of protein sequences and high-resolution 3D structures...
Led by Josep Lluis Gelpi, the node’s main purpose is to facilitate access to biological databases and programs by the bioinformatics community and to support the research Groups in the program...
Led by Montse Soler (IRB-BSC), this platform was established in January 2008 as part of the collaborative research program between the Institute of Research in Biomedicine (IRB Barcelona) and the...

Main Program Activities 2008

During 2008 the collaboration with the DEISA project was continued. A 3-year-evaluation of the BSC-CNS nodes by Genoma España was successfully passed. The responsibility to deal with the...
The agreement for the creation of the Joint Research Program was a milestone in the development of computational biology in Barcelona. Consolidation of the program was priority #1 for the program...